Jacquelyn L. (Mainville) Barthelette, 78, died Sunday May 19th in Baystate Medical Center. She was born in Holyoke, daughter of the late Alfred and Bella Mainville and graduated from Holyoke High School in 1964. She was a daycare teacher at Chicopee Child Development Center and also worked with her husband at Vanguard Moving and Storage. Jacquelyn was a communicant of St. Patrick's Church and enjoyed her summer home in Randolph, VT. She leaves her husband of 59 years Ronald Barthelette, a son Ronald Jr. of Chicopee, a daughter Christina Lever and her husband Brian of Medford, a daughter-in-law Pamela Barthelette of East Longmeadow and six grandchildren Michael, Taylor, Connor, Devon, Julie, and Joseph.  She was predeceased by her son Keith who passed on August 24, 2021. The funeral will be Friday May 24th at 9:00 am from the O'Brien Family Funeral Home, 33 Lamb St., South Hadley followed by Mass in St. Patrick's Church at 10:00 am. Burial in Notre Dame Cemetery. Calling hours are Thursday May 23rd from 5:00 to 7:00 pm. For more information or to make online condolences please go to obrienfamilyfh.com.